A happy man showing his eye and different sources of essetial fatty acids including nuts and omega 3 supplements.
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Misbah Wasi

Functional Nutrition Specialist, Scientific & Regulatory Advisor for Health Supplements

Misbah Wasi is a seasoned professional in the field of Nutrition Science and Food Regulation for over 15 years. Currently, she is lendin her expertise in the area of Health Supplements and Nutraceuticals and is an active member of the Standards Review Group (SRG) - Nutraceuticals FSSAI Ms. Wasi is a post-graduate in Food and Nutrition. Certified Lead Food Safety Management Systems Auditor (FSMS, FSSC 22000) and a certified FoSTaC traine for Health Supplements and Nutraceuticals. She is also a Subject Matter Expert for ‘Food Regulations in India’ for IFLR (International Food Laws and Regulations) course at Michigan State University.

Enhancing eye health with essential fatty acids

Eye health is crucial for overall well-being, and maintaining it becomes increasingly important as we age. One significant way to support eye health is through nutrition, particularly by incorporating essential fatty acids into our diet. Essential fatty acids, such as omega-3 and omega-6, play a pivotal role in maintaining the structural integrity and function of our eyes. In this blog, we will see the science behind essential fatty acids, their benefits for eye health, and practical ways to include them in your diet. [1]

Understanding Essential Fatty Acids

Essential fatty acids (EFAs) are types of polyunsaturated fats that our bodies cannot synthesize on their own. Therefore, we must obtain them through our diet. The two primary categories of EFAs are omega-3 and omega-6 fatty acids.

• Omega-3 Fatty Acids: These include alpha-linolenic acid (ALA), Eicosapentaenoic acid (EPA), and Docosahexaenoic acid (DHA). ALA is found in plant oils such as flaxseed and, in small quantities in hemp, walnut, canola, and soybean oil. It is typically present in the chloroplast of green leafy vegetables), while EPA and DHA are prevalent in marine oils, such as fish oil and algal oil. Fish and fish oil are the richest sources with contents ranging from 39 % to 50 % for both fresh and saltwater fish.


• Omega-6 Fatty Acids: Linoleic acid (LA) is the most common omega-6 fatty acid, found in many vegetable oils, nuts, and seeds. It is abundant in safflower, sunflower and corn, medium quantities in soybean, sesame, and almonds while canola, peanut and olive oils contain very small quantities. As per the need, our body converts LA into other fatty acids. The other omega-6 fatty acids are Gamma-linolenic acid (GLA), present in evening primrose oil and black current; Dihomo-gamma-linolenic acid, synthesized from GLA; and Arachidonic acid found in meat, eggs and dairy products.

Both types of EFAs are crucial for maintaining various bodily functions, including the development and maintenance of healthy eyes. [2]

Omega-3 benefits for the eyes

Numerous studies have highlighted the significant role that EFAs play in eye health. They contribute to several key aspects:

• Structural Integrity of Cell Membranes

DHA, an omega-3 fatty acid, is a major structural component of the retina. The retina is the light-sensitive layer at the back of the eye that plays a crucial role in vision. High concentrations of DHA are found in the photoreceptor cells, which are essential for converting light into nerve signals. A deficiency in DHA can lead to impaired vision and various eye disorders. [3]

• Reduction of Inflammation

Chronic inflammation is a common factor in many eye diseases, including age-related macular degeneration (AMD) and dry eye syndrome. Omega-3 fatty acids, particularly EPA and DHA, have anti-inflammatory properties that can help reduce eye inflammation. Studies have shown that these fatty acids can decrease the production of inflammatory cytokines and eicosanoids, which are linked to various inflammatory eye conditions. [4]

• Prevention of Age-Related Macular Degeneration (AMD)

AMD is a leading cause of vision loss in older adults. Research suggests that a diet rich in omega-3 fatty acids may lower the risk of developing AMD. A study published shows that higher intake of PUFA and MUFA is inversely associated with AMD. [5]

• Alleviation of Dry Eye Syndrome

Dry eye syndrome occurs when the eyes do not produce enough tears or when the tears evaporate too quickly. Omega-3 fatty acids can improve the quality of tears and reduce symptoms of dry eye. A study published in the American Journal of Clinical Nutrition demonstrated that participants who took omega-3 supplements experienced significant improvement in dry eye symptoms compared to those who took a placebo. [6]

 

• Delaying Glaucoma development

Glaucoma is a group of eye conditions that damage the optic nerve, often due to high intraocular pressure. Some studies suggest that omega-3 fatty acids may help reduce intraocular pressure, regulate blood supply, alleviate inflammation, and diminish oxidative stress, thereby potentially delaying the development of glaucoma.  [7,8]

How to Incorporate Essential Fatty Acids into Your Diet

To reap the eye health benefits of EFAs, it's important to include sources of omega-3 and omega-6 fatty acids in your diet. Here are some practical tips:

✔ Eat Fatty Fish

Fatty fish such as salmon, mackerel, sardines, and trout are excellent sources of EPA and DHA. Aim to include these fish in your diet at least twice a week.

✔ Use Plant Oils

For omega-6 fatty acids, use oils such as sunflower oil, safflower oil, and corn oil in your cooking. These oils are rich in linoleic acid, an essential omega-6 fatty acid.

✔ Incorporate Nuts and Seeds

Flaxseeds, chia seeds, walnuts, and hemp seeds are rich sources of ALA, a type of omega-3 fatty acid. Adding these to your diet can help ensure you get enough omega-3s.

✔ Consider Supplements

If you find it challenging to get enough omega-3 fatty acids from your diet alone, consider taking omega-3 fish oil supplements or algae-based supplements. These can provide concentrated doses of EPA and DHA.

✔ Balance Your Omega-6 Intake

While omega-6 fatty acids are important, it's crucial to maintain a proper balance between omega-3 and omega-6 intake. The typical Western diet tends to be high in omega-6 fatty acids and low in omega-3s. Aim for a balanced ratio to optimize your health benefits.

Maintaining eye health is a multifaceted endeavour, and essential fatty acids play a critical role in this process. From supporting the structural integrity of the retina to reducing inflammation and potentially preventing eye diseases like AMD and dry eye syndrome, the benefits of omega-3 and omega-6 fatty acids are well-documented. By incorporating sources of these essential fats into your diet, you can take proactive steps toward preserving your vision and ensuring your eyes remain healthy throughout your life.

For those looking to boost their eye health through diet, it’s essential to focus on a balanced intake of both omega-3 and omega-6 fatty acids. Whether through natural food sources or supplements, ensuring you get enough of these crucial nutrients can make a significant difference in your overall eye health. By integrating essential fatty acids into your diet, you can take a significant step toward maintaining and enhancing your eye health. As always, it's advisable to consult with a healthcare professional before making any major changes to your diet or starting new supplements.
 

References:

 

  1. Lawrenson JG, Downie LE. Nutrition and eye health. Nutrients. 2019 Sep 2.

  2. Kaur N, Chugh V, Gupta AK. Essential fatty acids as functional components of foods - a review. J Food Sci Technol. 2014.

  3. SanGiovanni JP, Chew EY. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res. 2005 Jan;24(1):87-138.

  4. Wang H, Daggy BP. The role of fish oil in inflammatory eye diseases. Biomed Hub. 2017 Jan-Apr;2(1):1-12.

  5. Higher intake of polyunsaturated fatty acid and monounsaturated fatty acid is inversely associated with AMD. Clin Epidemiol Res. 2020 Feb.

  6. Wang WX, Ko ML. Efficacy of omega-3 intake in managing dry eye disease: a systematic review and meta-analysis of randomized controlled trials. J Clin Med. 2023.

  7. Downie LE, Vingrys AJ. Oral omega-3 supplementation lowers intraocular pressure in normotensive adults. Transl Vis Sci Technol. 2018 May;7(3):1.

  8. Ye H, Liu Y, Xu Z, Wei X. Fish oil in glaucoma treatment: From biological functions to clinical potential. Molecular Nutrition & Food Research. 2023 Jun;67(11):2200727.
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